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Some diabetes drugs may come with added risk

>Some North Carolina diabetes patients could be at increased risk for a life-threatening complication called ketoacidosis if they take certain drugs to treate their disease. A study is warning that prescription medications like Invokana, Invokamet, Farxiga, Jardiance or Glyxambi could increase the risk.

In 2015, the U.S. Food and Drug Administration issued a warning about risks of diabetic ketoacidosis linked to the drugs. The complication can cause vomiting, shortness of breath, pain in the abdomen and brain swelling. While the condition usually occurs in people who have type 1 diabetes, it is rare yet possible with type 2 diabetes as well.

The study looked at 40,000 people with type 2 diabetes and found that people taking these drugs were twice as likely to develop the dangerous complication as those taking another type of diabetes drug. The rate of the complication is still quite low and the drugs are still useful for many patients. It is important to monitor patients for symptoms of the complication, especially if they are otherwise sick or ill.

Because the complication is typically associated with type 1 diabetes, type 2 diabetes patients may not be monitored for diabetic ketoacidosis. More people than recognized could have experienced the complication because of misdiagnosis or under-reporting among these patients.

A patient who has suffered serious complications due to diabetic ketoacidosis after taking an SLGT2 inhibitor may want to talk with a medical malpractice attorney about whether negligence played a role. The study makes clear attention by physicians to this complication can play a significant role in cutting risk as well as avoiding serious harm . A physician who failed to monitor a diabetes patient for this complication after prescribing this class of drug could potentially be responsible for a worsened medical condition as a result of side effects.

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